Optimal row–column design for three treatments

Optimal Row-Column Design for Three Treatments

The A-optimality problem is solved for three treatments in a row-column layout. Depending on the numbers of rows and columns, the requirements for optimality can be decidedly counterintuitive: replication numbers need not be as equal as possible, and trace of the information matrix need not be maximal. General rules for comparing 3 × 3 information matrices for their A-behavior are also develope...

E-optimal Designs for Three Treatments

E-optimality is studied for three treatments in an arbitrary n-way heterogeneity setting. In some cases maximal trace designs cannot be E-optimal. When there is more than one E-optimal design for a given setting, the best with respect to all reasonable criteria is determined.

Optimal Design for Purcell Three-link Swimmer

Optimal treatments for photodynamic therapy

Photodynamic therapy is a complex treatment for neoplastic diseases that uses the light-harvesting properties of a photosensitizer. The treatment depends on the amount of photosensitizer in the tissue and on the amount of light that is focused on the targeted area. We use a pharmacokinetic model to represent a photosensitizer’s movement through the anatomy and design treatments with a linear pr...

Determination of Optimal Sampling Design for Spatial Data Analysis

Extended Abstract. Inferences for spatial data are affected substantially by the spatial configuration of the network of sites where measurements are taken. Consider the following standard data-model framework for spatial data. Suppose a continuous, spatially-varying quantity, Z, is to be observed at a predetermined number, n, of points ....[ To Countinue Click here]